Not all roleplaying adventuring parties are fantasy based. We ran a short-live (no pun intended) but incredibly fun Zombpocalypse game using the d20 Modern rules some time ago.
Our GM, Rucht, threw some interesting curve-balls in on us and turned what we thought was a run-of-the-mill zombie romp into something a bit more creative.
I believe we all ended up on a boat, marooned at sea, unaware that the zombies were approaching us underwater. Like I said, lots of fun, and any game where the GM has you make a back-up character at the same time as your regular character you know things are going to be rough!
My first character, a thuggish, street-wise hooligan is on the left here. He was eaten by zombies fairly quickly. In the middle we have the local preacher, armed with a buzz saw and revolver, he was a zombie-whacking machine. Speaking of whacking, on the right was a local professional baseball player armed with his bat. He could also throw baseballs with deadly accuracy. A rag-tag bunch of survivors indeed.